Quote of the Day
I like opera, I just don't want to be around the people who like opera.
— Justice Clarence Thomas, during a discussion of Justice Scalia and Scalia's love of opera. I also have experienced being around engineers who love opera – Justice Thomas is correct.
During my editing of a previous post on heart power, which assumed that the heart converts chemical to mechanical energy with an efficiency of 20%, I found some other information on the web that would allow me to estimate the heart's conversion efficiency. I always like to do calculations that cross-check one-another to ensure that my information is consistent. This post documents my heart efficiency estimation exercise.
I was impressed with the wide variation that exists in the heart's physical parameters between individuals. This analysis is going to be rough because of the wide variability in these heart parameters.
The analysis approach is basic.
- Using information on the chemistry of food, determine the amount of energy produced by carbohydrates, proteins, and fats for every mL of O2.
This information is well documented from numerous source (example). The amount of energy available per liter of O2 varies with the type of carbohydrate (e.g. glucose, fructose), fat (e.g. stearate, palmitate), or protein (e.g. alanine, aspartate).
- Determine how much of the food energy is actually available for pumping versus heat generation and keeping cells alive.
This is measured value and it will vary widely based on the individual and the heart's activity level.
- Obtain the oxygen input to the heart.
This value has to measured under laboratory conditions.
- Compute the chemical power consumed by the heart and compare it to the mechanical work generated by the heart.
Given a specific heart size, food mix, and O2 consumption rate, we can determine the rate of chemical energy production. Since I computed the mechanical pumping power here, we can compute the efficiency.
Heart's Work Per mL of Oxygen
Figure 2 shows how to obtain an estimate for the average work performed by the heart per mL of O2. Notice how the number varies with the composition of the nutrients (carbohydrates, fats, proteins) that are feeding the heart.
Heat and Cell Overhead Losses
Figure 3 shows the numbers I found for the energy losses the heart experiences because of heat generation and cell overhead (i.e. keeping heart cells alive).
Chemical-to-Mechanical Efficiency Calculation
In this post, I estimated the heart's mechanical output power at 1.3 W. We can use this number along with the average heart size and oxygen consumption to estimate the chemical-to-mechanical conversion efficiency (Figure 4).
I compute an efficiency of 22%, a number that is highly dependent on a number of assumptions.
My plan for this post was to use some basic physics and a few pieces of information from the web to estimate the heart's chemical-to-mechanical conversion efficiency. My estimate of 22% is in within 20% to 25% range given by numerous sources. This demonstrates that the information I have been reading is internally consistent.